What Is PRP? How It Works for Skin and Hair, and What to Expect
What is PRP?
PRP (platelet-rich plasma) is plasma with a raised platelet concentration obtained from your own blood. A small sample is drawn, separated by centrifuge, and the platelet-rich fraction is delivered to the target area.
Platelets carry growth factors (PDGF, VEGF, TGF-β, EGF, IGF). These stimulate cell proliferation, collagen production and vascularisation, supporting tissue repair and renewal. Being autologous, allergy and rejection risk is very low.
Where is it used?
1) Skin rejuvenation
- Skin quality, glow and tone
- Fine lines and overall tissue vitality
- Thin under-eye skin support (in suitable candidates)
- Can be combined with microneedling or mesotherapy
2) Hair loss
- Early–mid stage androgenetic and telogen shedding
- Strengthens existing follicles, slows shedding, improves hair quality
- Can support graft survival after hair transplant
Important: PRP does not create new follicles in a bald area. It is ineffective in fully closed (cicatricial/advanced) zones; realistic candidate selection drives the result.
PRP or mesotherapy?
They work by different logic and often complement each other:
| PRP | Mesotherapy | |
|---|---|---|
| Source | Your own blood (autologous) | Ready vitamin/amino-acid/HA mix |
| Mechanism | Growth-factor renewal | Nutrient/hydration support |
| Allergy risk | Very low (autologous) | Depends on contents |
Which suits you depends on your goal; see our face mesotherapy vs PRP decision-matrix post.
Session plan and duration
- Initial course: typically 3–4 sessions, 3–4 weeks apart.
- Maintenance: every 6–12 months depending on result and area.
- Results are gradual; real assessment is usually after the course is complete.
The procedure takes 30–45 minutes (draw + prep + application), well tolerated with topical anaesthetic. Mild redness/swelling afterwards lasts hours to a couple of days.
Safety / who is unsuitable
Autologous sourcing is a safety advantage, but PRP is unsuitable or needs assessment in: blood/clotting disorders and platelet dysfunction; active infection (including skin infection at the site); some cancers and immunosuppressive therapy (physician assessment); pregnancy/breastfeeding (limited evidence — discuss with your physician).
FAQ
“When will I see results?” Skin glow in 2–4 weeks, clearer tissue improvement by the end of the course. For hair, slowed shedding first, thickening over a few months.
“Does it hurt?” Comfortable with topical anaesthetic; brief scalp tenderness is possible.
“Is it permanent?” PRP supports renewal but does not stop ageing/genetic hair loss; maintenance is needed.
“Is one session enough?” Usually no — it is supportive, not curative; planned as a course plus maintenance.
References
- Alves R, Grimalt R — A review of platelet-rich plasma: history, biology, mechanism of action
- Gentile P, et al. — PRP in androgenetic alopecia: randomized evaluation
- Hesseler MJ, Shyam N — PRP in cutaneous medicine: systematic review
- TİTCK / Sağlık Bakanlığı — otolog PRP uygulama bilgilendirmesi
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